3ZL2

A thiazolyl-mannoside bound to FimH, orthorhombic space group

Summary for 3ZL2

Entry DOI	10.2210/pdb3zl2/pdb
Related	3ZL1
Descriptor	PROTEIN FIMH, N-{5-[(1R)-1-hydroxyethyl]-1,3-thiazol-2-yl}-alpha-D-mannopyranosylamine (3 entities in total)
Functional Keywords	cell adhesion, type-1 fimbriae, thiazole, crohn's disease, immunoglobulin
Biological source	ESCHERICHIA COLI
Cellular location	Fimbrium: P08191
Total number of polymer chains	1
Total formula weight	17221.15
Authors	Brument, S.,Sivignon, A.,Dumych, T.I.,Moreau, N.,Roos, G.,Guerardel, Y.,Chalopin, T.,Deniaud, D.,Bilyy, R.O.,Darfeuille-Michaud, A.,Bouckaert, J.,Gouin, S.G. (deposition date: 2013-01-27, release date: 2013-07-10, Last modification date: 2023-12-20)
Primary citation	Brument, S.,Sivignon, A.,Dumych, T.I.,Moreau, N.,Roos, G.,Guerardel, Y.,Chalopin, T.,Deniaud, D.,Bilyy, R.O.,Darfeuille-Michaud, A.,Bouckaert, J.,Gouin, S.G. Thiazolylaminomannosides as Potent Antiadhesives of Type 1 Piliated Escherichia Coli Isolated from Crohn'S Disease Patients. J.Med.Chem., 56:5395-, 2013 Cited by PubMed: 23795713 DOI: 10.1021/JM400723N PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.251 Å)

Structure validation