3ZHV

Crystal structure of the SucA domain of Mycobacterium smegmatis KGD, post-decarboxylation intermediate from pyruvate (2-hydroxyethyl-ThDP)

Summary for 3ZHV

Entry DOI	10.2210/pdb3zhv/pdb
Related	3ZHQ 3ZHR 3ZHS 3ZHT 3ZHU
Descriptor	MULTIFUNCTIONAL 2-OXOGLUTARATE METABOLISM ENZYME, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-[(1S)-1-oxidanylethyl]-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	oxidoreductase, e1o
Biological source	MYCOBACTERIUM SMEGMATIS
Total number of polymer chains	4
Total formula weight	390801.59
Authors	Wagner, T.,Barilone, N.,Bellinzoni, M.,Alzari, P.M. (deposition date: 2012-12-24, release date: 2013-11-13, Last modification date: 2023-12-20)
Primary citation	Wagner, T.,Barilone, N.,Alzari, P.M.,Bellinzoni, M. A Dual Conformation of the Post-Decarboxylation Intermediate is Associated with Distinct Enzyme States in Mycobacterial Alpha-Ketoglutarate Decarboxylase (Kgd). Biochem.J., 457:425-, 2014 Cited by PubMed: 24171907 DOI: 10.1042/BJ20131142 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation