3ZGZ

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and toxic moiety from agrocin 84 (TM84) in aminoacylation-like conformation

Summary for 3ZGZ

Entry DOI	10.2210/pdb3zgz/pdb
Descriptor	LEUCINE--TRNA LIGASE, TRNA-LEU UAA ISOACCEPTOR, ZINC ION, ... (6 entities in total)
Functional Keywords	ligase-rna complex, ligase, nucleotide(atp)-binding, protein biosynthesis, class i aminoacyl-trna synthetase, ligase/rna
Biological source	ESCHERICHIA COLI More
Cellular location	Cytoplasm: P07813
Total number of polymer chains	4
Total formula weight	257047.49
Authors	Chopra, S.,Palencia, A.,Virus, C.,Tripathy, A.,Temple, B.R.,Velazquez-Campoy, A.,Cusack, S.,Reader, J.S. (deposition date: 2012-12-19, release date: 2013-01-30, Last modification date: 2023-12-20)
Primary citation	Chopra, S.,Palencia, A.,Virus, C.,Tripathy, A.,Temple, B.R.,Velazquez-Campoy, A.,Cusack, S.,Reader, J.S. Plant Tumour Biocontrol Agent Employs a tRNA-Dependent Mechanism to Inhibit Leucyl-tRNA Synthetase Nat.Commun., 4:1417-, 2013 Cited by PubMed: 23361008 DOI: 10.1038/NCOMMS2421 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation