3ZGN
Crystal structures of Escherichia coli IspH in complex with TMBPP a potent inhibitor of the methylerythritol phosphate pathway
Summary for 3ZGN
Entry DOI | 10.2210/pdb3zgn/pdb |
Related | 3ZGL |
Descriptor | 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, (2E)-3-methyl-4-sulfanylbut-2-en-1-yl trihydrogen diphosphate, IRON/SULFUR CLUSTER, ... (4 entities in total) |
Functional Keywords | oxidoreductase, mep pathway, inhibitors, 4fe-4s cluster |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 2 |
Total formula weight | 74538.63 |
Authors | Borel, F.,Barbier, E.,Kratsutsky, S.,Janthawornpong, K.,Rohmer, M.,Dale Poulter, C.,Ferrer, J.L.,Seemann, M. (deposition date: 2012-12-18, release date: 2013-01-09, Last modification date: 2023-12-20) |
Primary citation | Borel, F.,Barbier, E.,Krasutsky, S.,Janthawornpong, K.,Chaignon, P.,Poulter, C.D.,Ferrer, J.L.,Seemann, M. Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New Antimicrobials. Chembiochem, 18:2137-2144, 2017 Cited by PubMed: 28862365DOI: 10.1002/cbic.201700363 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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