3ZCZ

Crystal structure of a complex between Actinomadura R39 DD-peptidase and a trifluoroketone inhibitor

Summary for 3ZCZ

Entry DOI	10.2210/pdb3zcz/pdb
Descriptor	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, (2R)-2-amino-7-oxo-7-{[(2R,3S)-4,4,4-trifluoro-3-hydroxybutan-2-yl]amino}heptanoic acid, SULFATE ION, ... (5 entities in total)
Functional Keywords	hydrolase, inhibitor, peptidoglycan
Biological source	ACTINOMADURA SP. R39
Cellular location	Secreted: P39045
Total number of polymer chains	4
Total formula weight	193843.67
Authors	Sauvage, E.,Herman, R.,Kerff, F.,Rocaboy, M.,Charlier, P. (deposition date: 2012-11-23, release date: 2013-03-27, Last modification date: 2023-12-20)
Primary citation	Dzhekieva, L.,Adediran, S.A.,Herman, R.,Kerff, F.,Duez, C.,Charlier, P.,Sauvage, E.,Pratt, R.F. Inhibition of Dd-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 Dd-Peptidase. Biochemistry, 52:2128-, 2013 Cited by PubMed: 23484909 DOI: 10.1021/BI400048S PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation