3X1I
hPPARgamma Ligand binding domain in complex with 6-oxo-tetracosahexaenoic acid
Summary for 3X1I
| Entry DOI | 10.2210/pdb3x1i/pdb |
| Related | 3X1H |
| Descriptor | Peroxisome proliferator-activated receptor gamma, (8E,12Z,15Z,18Z,21Z)-6-oxotetracosa-8,12,15,18,21-pentaenoic acid (3 entities in total) |
| Functional Keywords | nuclear receptor, transcription regulation, ligand binding domain, diabetes mellitus, zinc-finger, dna-binding, transcription, obesity |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: P37231 |
| Total number of polymer chains | 2 |
| Total formula weight | 63644.12 |
| Authors | Egawa, D.,Itoh, T.,Yamamoto, K. (deposition date: 2014-11-18, release date: 2015-04-08, Last modification date: 2022-08-24) |
| Primary citation | Egawa, D.,Itoh, T.,Yamamoto, K. Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids. Bioconjug.Chem., 26:690-698, 2015 Cited by PubMed: 25785518DOI: 10.1021/acs.bioconjchem.5b00021 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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