3WPD

Crystal structure of horse TLR9 in complex with inhibitory DNA4084

Summary for 3WPD

• Entry DOI: 10.2210/pdb3wpd/pdb
• Related: 3WPB 3WPC 3WPE 3WPF 3WPG 3WPH 3WPI
• Descriptor: Toll-like receptor 9, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*G)-3'), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: leucine rich repeat, receptor, innate immunity, dna binding, glycosylation, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Equus caballus (horse); More
• Total number of polymer chains: 2
• Total formula weight: 93683.60

Authors

Ohto, U.,Tanji, H.,Shimizu, T. (deposition date: 2014-01-11, release date: 2015-02-11, Last modification date: 2020-07-29)

• Primary citation: Ohto, U.,Shibata, T.,Tanji, H.,Ishida, H.,Krayukhina, E.,Uchiyama, S.,Miyake, K.,Shimizu, T.; Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9; Nature, 520:702-705, 2015; PubMed: 25686612; DOI: 10.1038/nature14138

Experimental method

X-RAY DIFFRACTION (2.75 Å)