3WN7
Crystal Structure of Keap1 in Complex with the N-terminal region of the Nrf2 transcription factor
Summary for 3WN7
| Entry DOI | 10.2210/pdb3wn7/pdb |
| Descriptor | Kelch-like ECH-associated protein 1, Peptide from Nuclear factor erythroid 2-related factor 2, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | beta-propeller, kelch motif, degron, transcription |
| Biological source | Mus musculus (mouse) More |
| Cellular location | Cytoplasm: Q9Z2X8 Cytoplasm, cytosol: Q60795 |
| Total number of polymer chains | 4 |
| Total formula weight | 77327.99 |
| Authors | Fukutomi, T.,Takagi, K.,Mizushima, T.,Ohuchi, N.,Yamamoto, M. (deposition date: 2013-12-05, release date: 2013-12-25, Last modification date: 2023-11-08) |
| Primary citation | Fukutomi, T.,Takagi, K.,Mizushima, T.,Ohuchi, N.,Yamamoto, M. Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1 Mol.Cell.Biol., 34:832-846, 2014 Cited by PubMed: 24366543DOI: 10.1128/MCB.01191-13 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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