3VVP

Crystal structure of MATE in complex with Br-NRF

Summary for 3VVP

Entry DOI	10.2210/pdb3vvp/pdb
Related	3VVN 3VVO 3VVQ 3VVR 3VVS
Descriptor	Putative uncharacterized protein, 6-bromo-1-ethyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (3 entities in total)
Functional Keywords	mate, multidrug transporter, ligand-bound, transport protein
Biological source	Pyrococcus furiosus
Total number of polymer chains	2
Total formula weight	98932.75
Authors	Tanaka, Y.,Ishitani, R.,Nureki, O. (deposition date: 2012-07-27, release date: 2013-04-03, Last modification date: 2023-11-08)
Primary citation	Tanaka, Y.,Hipolito, C.J.,Maturana, A.D.,Ito, K.,Kuroda, T.,Higuchi, T.,Katoh, T.,Kato, H.E.,Hattori, M.,Kumazaki, K.,Tsukazaki, T.,Ishitani, R.,Suga, H.,Nureki, O. Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496:247-251, 2013 Cited by PubMed: 23535598 DOI: 10.1038/nature12014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.91 Å)

Structure validation