3VVA

Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative

Summary for 3VVA

Entry DOI	10.2210/pdb3vva/pdb
Related	3VV9 3W54
Descriptor	Alternative oxidase, mitochondrial, FE (III) ION, HYDROXIDE ION, ... (5 entities in total)
Functional Keywords	helix double, membrane bound diiron protein, oxidase, membrane, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, alternative oxidase, oxidoreductase/oxidoreductase inhibitor
Biological source	Trypanosoma brucei brucei
Cellular location	Mitochondrion inner membrane; Multi-pass membrane protein (Probable): Q26710
Total number of polymer chains	4
Total formula weight	152499.35
Authors	Shiba, T.,Kido, Y.,Sakamoto, K.,Inaoka, D.K.,Tsuge, C.,Tatsumi, R.,Balogun, E.O.,Nara, T.,Aoki, T.,Honma, T.,Tanaka, A.,Inoue, M.,Matsuoka, S.,Saimoto, H.,Moore, A.L.,Harada, S.,Kita, K. (deposition date: 2012-07-17, release date: 2013-03-13, Last modification date: 2023-11-08)
Primary citation	Shiba, T.,Kido, Y.,Sakamoto, K.,Inaoka, D.K.,Tsuge, C.,Tatsumi, R.,Takahashi, G.,Balogun, E.O.,Nara, T.,Aoki, T.,Honma, T.,Tanaka, A.,Inoue, M.,Matsuoka, S.,Saimoto, H.,Moore, A.L.,Harada, S.,Kita, K. Structure of the trypanosome cyanide-insensitive alternative oxidase Proc.Natl.Acad.Sci.USA, 110:4580-4585, 2013 Cited by PubMed: 23487766 DOI: 10.1073/pnas.1218386110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation