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3VRT

VDR ligand binding domain in complex with 2-Mehylidene-19,25,26,27-tetranor-1alpha,24-dihydroxyvitaminD3

Summary for 3VRT
Entry DOI10.2210/pdb3vrt/pdb
Related3VRU 3VRV 3VRW
DescriptorVitamin D3 receptor, 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1, (1R,3R,7E,17beta)-17-[(2R)-5-hydroxypentan-2-yl]-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, ... (4 entities in total)
Functional Keywordstranscription, vitamin d3, vdre, rxr, co-factors, nuclear
Biological sourceRattus norvegicus (Rat)
More
Cellular locationNucleus: P13053 Q15648
Total number of polymer chains2
Total formula weight32540.49
Authors
Nakabayashi, M.,Yoshimoto, N.,Inaba, Y.,Itoh, T.,Ito, N.,Yamamoto, K. (deposition date: 2012-04-14, release date: 2012-05-23, Last modification date: 2024-03-20)
Primary citationYoshimoto, N.,Sakamaki, Y.,Haeta, M.,Kato, A.,Inaba, Y.,Itoh, T.,Nakabayashi, M.,Ito, N.,Yamamoto, K.
Butyl pocket formation in the vitamin d receptor strongly affects the agonistic or antagonistic behavior of ligands
J.Med.Chem., 55:4373-4381, 2012
Cited by
PubMed: 22512505
DOI: 10.1021/jm300230a
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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