3VQ2

Crystal structure of mouse TLR4/MD-2/LPS complex

Summary for 3VQ2

Entry DOI	10.2210/pdb3vq2/pdb
Related	3VQ1
Descriptor	Toll-like receptor 4, Lymphocyte antigen 96, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	leucine rich repeat md-2 related lipid recognition, receptor innate immunity, lipid binding, glycosylation, secreted, immune system
Biological source	Mus musculus (mouse) More
Total number of polymer chains	4
Total formula weight	175899.72
Authors	Ohto, U.,Shimizu, T. (deposition date: 2012-03-17, release date: 2012-05-09, Last modification date: 2023-11-08)
Primary citation	Ohto, U.,Fukase, K.,Miyake, K.,Shimizu, T. Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2 Proc.Natl.Acad.Sci.USA, 109:7421-7426, 2012 Cited by PubMed: 22532668 DOI: 10.1073/pnas.1201193109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation