3VI4

Crystal structure of alpha5beta1 integrin headpiece in complex with RGD peptide

Summary for 3VI4

• Entry DOI: 10.2210/pdb3vi4/pdb
• Descriptor: Integrin alpha-5, MAGNESIUM ION, Integrin beta-1, ... (10 entities in total)
• Functional Keywords: beta propeller fold, rossmann fold, beta sandwich, fibronectin receptor, cell adhesion-immune system complex, cell adhesion/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 339884.39

Authors

Nagae, M.,Nogi, T.,Takagi, J. (deposition date: 2011-09-21, release date: 2012-02-22, Last modification date: 2020-07-29)

• Primary citation: Nagae, M.,Re, S.,Mihara, E.,Nogi, T.,Sugita, Y.,Takagi, J.; Crystal structure of alpha5beta1 integrin ectodomain: Atomic details of the fibronectin receptor; J.Cell Biol., 197:131-140, 2012; PubMed: 22451694; DOI: 10.1083/jcb.201111077

Experimental method

X-RAY DIFFRACTION (2.9 Å)