3VGX

Structure of gp41 T21/Cp621-652

Summary for 3VGX

• Entry DOI: 10.2210/pdb3vgx/pdb
• Related: 3VGY 3VH7
• Descriptor: Envelope glycoprotein gp160, ACETIC ACID, GLYCEROL, ... (5 entities in total)
• Functional Keywords: 6-helix bundle, membrane fusion, membrane protein
• Biological source: Human immunodeficiency virus type 1 (HIV-1); More
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P03375 P03375
• Total number of polymer chains: 2
• Total formula weight: 8693.82

Authors

Yao, X.,Waltersperger, S.,Wang, M.,Cui, S. (deposition date: 2011-08-22, release date: 2012-04-25, Last modification date: 2023-11-08)

• Primary citation: Chong, H.,Yao, X.,Qiu, Z.,Qin, B.,Han, R.,Waltersperger, S.,Wang, M.,Cui, S.,He, Y.; Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.; J.Biol.Chem., 287:20281-20289, 2012; PubMed: 22511760; DOI: 10.1074/jbc.M112.354126

Experimental method

X-RAY DIFFRACTION (1.74 Å)