3VFG
Crystal structure of monoclonal antibody 3F8 Fab fragment that binds to GD2 ganglioside
Summary for 3VFG
| Entry DOI | 10.2210/pdb3vfg/pdb |
| Related | 1PSK 2AJU |
| Descriptor | 3F8 Light Chain, 3F8 Heavy Chain (3 entities in total) |
| Functional Keywords | immunoglobulin, antibody, gd2 ganglioside, immune system |
| Biological source | Mus musculus (mouse) More |
| Total number of polymer chains | 2 |
| Total formula weight | 46651.12 |
| Authors | Ahmed, M.,Goldgur, Y.,Cheung, N.-K. (deposition date: 2012-01-09, release date: 2013-02-06, Last modification date: 2023-09-13) |
| Primary citation | Ahmed, M.,Goldgur, Y.,Hu, J.,Guo, H.F.,Cheung, N.K. In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors. Plos One, 8:e63359-e63359, 2013 Cited by PubMed: 23696816DOI: 10.1371/journal.pone.0063359 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report
