3VD8

Crystal structure of human AIM2 PYD domain with MBP fusion

Summary for 3VD8

Entry DOI	10.2210/pdb3vd8/pdb
Related PRD ID	PRD_900010
Descriptor	Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	mbp/pyd/dd, signal transduction, inflammasome, sugar binding protein, signaling protein
Biological source	Escherichia coli (human) More
Total number of polymer chains	1
Total formula weight	55044.66
Authors	Jin, T.C.,Perry, A.,Smith, P.,Xiao, T.S. (deposition date: 2012-01-04, release date: 2013-01-16, Last modification date: 2023-09-13)
Primary citation	Jin, T.,Perry, A.,Smith, P.,Jiang, J.,Xiao, T.S. Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly. J.Biol.Chem., 288:13225-13235, 2013 Cited by PubMed: 23530044 DOI: 10.1074/jbc.M113.468033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.0685 Å)

Structure validation