3VAI

Structure of U2AF65 variant with BrU3C5 DNA

Summary for 3VAI

• Entry DOI: 10.2210/pdb3vai/pdb
• Related: 2G4B 2HZC 3VAF 3VAG 3VAH 3VAJ 3VAK 3VAL 3VAM 3VAN 3VAO
• Descriptor: Splicing factor U2AF 65 kDa subunit, DNA 5'-D(*UP*UP*(BRU)P*UP*CP*UP*U)-3', 1,4-DIETHYLENE DIOXIDE, ... (7 entities in total)
• Functional Keywords: rna splicing factor, rna recognition motif, rna binding protein, rna binding protein-dna complex, rna binding protein/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P26368
• Total number of polymer chains: 4
• Total formula weight: 44346.87

Authors

Jenkins, J.L.,Frato, K.H.,Kielkopf, C.L. (deposition date: 2011-12-29, release date: 2013-02-13, Last modification date: 2024-02-28)

• Primary citation: Jenkins, J.L.,Agrawal, A.A.,Gupta, A.,Green, M.R.,Kielkopf, C.L.; U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.; Nucleic Acids Res., 41:3859-3873, 2013; PubMed: 23376934; DOI: 10.1093/nar/gkt046

Experimental method

X-RAY DIFFRACTION (2.2 Å)