3V7X

Complex of human carbonic anhydrase II with N-[2-(3,4-dimethoxyphenyl)ethyl]-4-sulfamoylbenzamide

Summary for 3V7X

• Entry DOI: 10.2210/pdb3v7x/pdb
• Related: 3VBD
• Descriptor: Carbonic anhydrase 2, ZINC ION, N-[2-(3,4-dimethoxyphenyl)ethyl]-4-sulfamoylbenzamide, ... (6 entities in total)
• Functional Keywords: lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 31334.97

Authors

Mader, P.,Brynda, J.,Rezacova, P. (deposition date: 2011-12-22, release date: 2012-04-04, Last modification date: 2023-09-13)

• Primary citation: Gitto, R.,Damiano, F.M.,Mader, P.,De Luca, L.,Ferro, S.,Supuran, C.T.,Vullo, D.,Brynda, J.,Rezacova, P.,Chimirri, A.; Synthesis, Structure-Activity Relationship Studies, and X-ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors.; J.Med.Chem., 55:3891-3899, 2012; PubMed: 22443141; DOI: 10.1021/jm300112w

Experimental method

X-RAY DIFFRACTION (1.03 Å)