3V4O

Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor

Summary for 3V4O

• Entry DOI: 10.2210/pdb3v4o/pdb
• Related: 3V4L 3V55
• Related PRD ID: PRD_001076
• Descriptor: Mucosa-associated lymphoid tissue lymphoma translocation protein 1, MALT1 Inhibitor (3 entities in total)
• Functional Keywords: caspase, hydrolase, traf6, bcl10, cytosolic, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, perinuclear region : Q9UDY8
• Total number of polymer chains: 2
• Total formula weight: 28407.04

Authors

Renatus, M.,Wiesmann, C. (deposition date: 2011-12-15, release date: 2012-03-14, Last modification date: 2023-11-29)

• Primary citation: Wiesmann, C.,Leder, L.,Blank, J.,Bernardi, A.,Melkko, S.,Decock, A.,D'Arcy, A.,Villard, F.,Erbel, P.,Hughes, N.,Freuler, F.,Nikolay, R.,Alves, J.,Bornancin, F.,Renatus, M.; Structural Determinants of MALT1 Protease Activity.; J.Mol.Biol., 419:4-21, 2012; PubMed: 22366302; DOI: 10.1016/j.jmb.2012.02.018

Experimental method

X-RAY DIFFRACTION (2.1 Å)