3V1X

Crystal structure of 2-methylisoborneol synthase from Streptomyces coelicolor A3(2) in complex with Mg2+ and 2-fluorogeranyl diphosphate

Summary for 3V1X

• Entry DOI: 10.2210/pdb3v1x/pdb
• Related: 3V1V
• Descriptor: 2-methylisoborneol synthase, MAGNESIUM ION, (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, ... (4 entities in total)
• Functional Keywords: class i terpenoid cyclase fold, ddxxxxd motif, ndxxsxxxe motif, 2-methylisoborneol biosynthesis, biosynthesis of 2-methylisoborneol, lyase
• Biological source: Streptomyces coelicolor
• Total number of polymer chains: 1
• Total formula weight: 50525.71

Authors

Koksal, M.,Christianson, D.W. (deposition date: 2011-12-10, release date: 2012-04-11, Last modification date: 2023-09-13)

• Primary citation: Koksal, M.,Chou, W.K.,Cane, D.E.,Christianson, D.W.; Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C-Methylated Monoterpenoid Substrate.; Biochemistry, 51:3011-3020, 2012; PubMed: 22455514; DOI: 10.1021/bi201827a

Experimental method

X-RAY DIFFRACTION (1.955 Å)