3UZ5

Designed protein KE59 R13 3/11H

Summary for 3UZ5

• Entry DOI: 10.2210/pdb3uz5/pdb
• Related: 3UXA 3UXD 3UY7 3UY8 3UYC 3UZJ
• Descriptor: Kemp eliminase KE59 R13 3/11H, 5,7-dichloro-1H-benzotriazole, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: structural genomics, israel structural proteomics center, ispc, beta barrel, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 58312.11

Authors

Khersonsky, O.,Kiss, G.,Roethlisberger, D.,Dym, O.,Albeck, S.,Houk, K.N.,Baker, D.,Tawfik, D.S.,Israel Structural Proteomics Center (ISPC) (deposition date: 2011-12-07, release date: 2012-06-06, Last modification date: 2023-09-13)

• Primary citation: Khersonsky, O.,Kiss, G.,Rothlisberger, D.,Dym, O.,Albeck, S.,Houk, K.N.,Baker, D.,Tawfik, D.S.; Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59.; Proc.Natl.Acad.Sci.USA, 109:10358-10363, 2012; PubMed: 22685214; DOI: 10.1073/pnas.1121063109

Experimental method

X-RAY DIFFRACTION (1.9 Å)