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3UYO

Crystal structure of monobody SH13/ABL1 SH2 domain complex

Summary for 3UYO
Entry DOI10.2210/pdb3uyo/pdb
Related3K2M 3NCS
DescriptorTyrosine-protein kinase ABL1, Monobody SH13, SULFATE ION, ... (4 entities in total)
Functional Keywordsengineered binding protein, antibody mimic, protein-protein complex, sh2 domain, atp-binding, phosphoprotein, tyrosine-protein kinase, signaling protein-protein binding complex, signaling protein/protein binding
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
Total number of polymer chains2
Total formula weight23872.24
Authors
Wojcik, J.B.,Koide, A.,Koide, S. (deposition date: 2011-12-06, release date: 2011-12-28, Last modification date: 2023-09-13)
Primary citationKoide, A.,Wojcik, J.,Gilbreth, R.N.,Hoey, R.J.,Koide, S.
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold.
J.Mol.Biol., 415:393-405, 2012
Cited by
PubMed: 22198408
DOI: 10.1016/j.jmb.2011.12.019
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.83 Å)
Structure validation

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