3UEO

Crystal structure of TopBP1 BRCT4/5 domains in complex with a phospho-peptide

Summary for 3UEO

• Entry DOI: 10.2210/pdb3ueo/pdb
• Related: 3UEN
• Descriptor: DNA topoisomerase 2-binding protein 1, phospho-peptide (3 entities in total)
• Functional Keywords: brct domain, phospho-peptide binding, peptide binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q92547
• Total number of polymer chains: 6
• Total formula weight: 91984.03

Authors

Leung, C.C.,Glover, J.N.M. (deposition date: 2011-10-31, release date: 2013-07-03, Last modification date: 2014-03-26)

• Primary citation: Leung, C.C.,Sun, L.,Gong, Z.,Burkat, M.,Edwards, R.,Assmus, M.,Chen, J.,Glover, J.N.; Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.; Structure, 21:1450-1459, 2013; PubMed: 23891287; DOI: 10.1016/j.str.2013.06.015

Experimental method

X-RAY DIFFRACTION (2.6 Å)