3TWH

Selenium Derivatized RNA/DNA Hybrid in complex with RNase H Catalytic Domain D132N Mutant

Summary for 3TWH

• Entry DOI: 10.2210/pdb3twh/pdb
• Related: 1ZBI 2G8U
• Descriptor: Ribonuclease H, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), DNA (5'-D(*AP*TP*(SDG)P*TP*CP*(SDG))-3'), ... (6 entities in total)
• Functional Keywords: selenium-dna/rna, rnase h, endonuclease, hydrolase, magnesium, manganese, metal-binding, selenium-modification, hydrolase-rna-dna complex, hydrolase/rna/dna
• Biological source: Bacillus halodurans
• Cellular location: Cytoplasm (Potential): Q9KEI9
• Total number of polymer chains: 3
• Total formula weight: 19884.92

Authors

Rob, A.,Gerlits, O.,Jiang, J.S.,Gan, J.H.,Huang, Z. (deposition date: 2011-09-21, release date: 2012-10-03, Last modification date: 2024-02-28)

• Primary citation: Abdur, R.,Gerlits, O.O.,Gan, J.,Jiang, J.,Salon, J.,Kovalevsky, A.Y.,Chumanevich, A.A.,Weber, I.T.,Huang, Z.; Novel complex MAD phasing and RNase H structural insights using selenium oligonucleotides.; Acta Crystallogr.,Sect.D, 70:354-361, 2014; PubMed: 24531469; DOI: 10.1107/S1399004713027922

Experimental method

X-RAY DIFFRACTION (1.79 Å)