3TMJ

Joint X-ray/neutron structure of human carbonic anhydrase II at pH 7.8

Summary for 3TMJ

• Entry DOI: 10.2210/pdb3tmj/pdb
• Descriptor: Carbonic anhydrase 2, ZINC ION (3 entities in total)
• Functional Keywords: h/d exchanged, joint neutron/x-ray refinement, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 29136.19

Authors

Fisher, Z. (deposition date: 2011-08-31, release date: 2011-11-09, Last modification date: 2023-09-13)

• Primary citation: Fisher, Z.,Kovalevsky, A.Y.,Mustyakimov, M.,Silverman, D.N.,McKenna, R.,Langan, P.; Neutron Structure of Human Carbonic Anhydrase II: A Hydrogen-Bonded Water Network "Switch" Is Observed between pH 7.8 and 10.0.; Biochemistry, 50:9421-9423, 2011; PubMed: 21988105; DOI: 10.1021/bi201487b

Experimental method

NEUTRON DIFFRACTION (2 Å)
X-RAY DIFFRACTION