3TIY
CDK2 in complex with NSC 35676
Summary for 3TIY
| Entry DOI | 10.2210/pdb3tiy/pdb |
| Related | 3TI1 3TIZ |
| Descriptor | Cyclin-dependent kinase 2, 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, ... (4 entities in total) |
| Functional Keywords | protein kinase, allosteric ligand, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, cytoskeleton, centrosome: P24941 |
| Total number of polymer chains | 1 |
| Total formula weight | 34941.48 |
| Authors | Alam, R.,Schonbrunn, E. (deposition date: 2011-08-22, release date: 2012-08-22, Last modification date: 2024-02-28) |
| Primary citation | Martin, M.P.,Alam, R.,Betzi, S.,Ingles, D.J.,Zhu, J.Y.,Schonbrunn, E. A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13:2128-2136, 2012 Cited by PubMed: 22893598DOI: 10.1002/cbic.201200316 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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