3TGS

Crystal structure of HIV-1 clade C strain C1086 gp120 core in complex with NBD-556

Summary for 3TGS

Entry DOI	10.2210/pdb3tgs/pdb
Related	3TGQ 3TGR 3TGT 3TIH
Descriptor	HIV-1 clade C1086 gp120 core, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-(4-chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)ethanediamide, ... (4 entities in total)
Functional Keywords	hiv-1 gp120, clade c1086, complex, nbd-556, viral protein
Biological source	Human immunodeficiency virus 1 (HIV-1)
Total number of polymer chains	2
Total formula weight	83062.72
Authors	Kwon, Y.D.,Kwong, P.D. (deposition date: 2011-08-17, release date: 2012-04-04, Last modification date: 2020-07-29)
Primary citation	Kwon, Y.D.,Finzi, A.,Wu, X.,Dogo-Isonagie, C.,Lee, L.K.,Moore, L.R.,Schmidt, S.D.,Stuckey, J.,Yang, Y.,Zhou, T.,Zhu, J.,Vicic, D.A.,Debnath, A.K.,Shapiro, L.,Bewley, C.A.,Mascola, J.R.,Sodroski, J.G.,Kwong, P.D. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc.Natl.Acad.Sci.USA, 109:5663-5668, 2012 Cited by PubMed: 22451932 DOI: 10.1073/pnas.1112391109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation