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3TGS

Crystal structure of HIV-1 clade C strain C1086 gp120 core in complex with NBD-556

Summary for 3TGS

Related3TGQ 3TGR 3TGT 3TIH 
DescriptorHIV-1 clade C1086 gp120 core
Functional KeywordsHIV-1 gp120, clade C1086, complex, NBD-556, VIRAL PROTEIN,VIRAL PROTEIN
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
Total number of polymer chains2
Total molecular weight83063.44
Authors
Kwon, Y.D.,Kwong, P.D. (deposition date: 2011-08-17, release date: 2012-04-04, modification date: 2014-12-17)
Primary citation
Kwon, Y.D.,Finzi, A.,Wu, X.,Dogo-Isonagie, C.,Lee, L.K.,Moore, L.R.,Schmidt, S.D.,Stuckey, J.,Yang, Y.,Zhou, T.,Zhu, J.,Vicic, D.A.,Debnath, A.K.,Shapiro, L.,Bewley, C.A.,Mascola, J.R.,Sodroski, J.G.,Kwong, P.D.
Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc.Natl.Acad.Sci.USA, 109:5663-5668, 2012
PubMed: 22451932
DOI: 10.1073/pnas.1112391109
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersCα geometrySidechain outliersRSRZ outliers0.281190.6%3.6%4.4%8.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolutionDownload full validation report

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105097
entries available on 2014-12-17
00:00 UTC / 09:00 JST