3T5E

Crystal structure of an intramolecular human telomeric DNA G-quadruplex bound by the naphthalene diimide BMSG-SH-4

Summary for 3T5E

Entry DOI	10.2210/pdb3t5e/pdb
Related	1KF1 3SC8
Descriptor	human telomeric DNA sequence, 2,7-bis[4-(4-methylpiperazin-1-yl)butyl]-4,9-bis{[4-(4-methylpiperazin-1-yl)butyl]amino}benzo[lmn][3,8]phenanthroline-1 ,3,6,8(2H,7H)-tetrone, POTASSIUM ION, ... (4 entities in total)
Functional Keywords	g-quadruplex, intramolecular, ligand-complex, telomeric, dna
Total number of polymer chains	1
Total formula weight	8014.04
Authors	Collie, G.W.,Promontorio, R.,Parkinson, G.N. (deposition date: 2011-07-27, release date: 2012-02-15, Last modification date: 2023-09-13)
Primary citation	Collie, G.W.,Promontorio, R.,Hampel, S.M.,Micco, M.,Neidle, S.,Parkinson, G.N. Structural basis for telomeric g-quadruplex targeting by naphthalene diimide ligands. J.Am.Chem.Soc., 134:2723-2731, 2012 Cited by PubMed: 22280460 DOI: 10.1021/ja2102423 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation