3T3S

Human Cytochrome P450 2A13 in complex with Pilocarpine

Summary for 3T3S

• Entry DOI: 10.2210/pdb3t3s/pdb
• Related: 2P85 3T3Q 3T3R 3T3Z
• Descriptor: Cytochrome P450 2A13, PROTOPORPHYRIN IX CONTAINING FE, (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, ... (4 entities in total)
• Functional Keywords: cyp2a13, cytochrome p450 2a13, p450 2a13, heme protein, monooxygenase, drug metabolism, xenobiotic metabolism, endoplasmic reticulum, membrane, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum membrane; Peripheral membrane protein: Q16696
• Total number of polymer chains: 8
• Total formula weight: 444619.50

Authors

DeVore, N.M.,Scott, E.E. (deposition date: 2011-07-25, release date: 2011-12-07, Last modification date: 2023-09-13)

• Primary citation: DeVore, N.M.,Meneely, K.M.,Bart, A.G.,Stephens, E.S.,Battaile, K.P.,Scott, E.E.; Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine.; Febs J., 279:1621-1631, 2012; PubMed: 22051186; DOI: 10.1111/j.1742-4658.2011.08412.x

Experimental method

X-RAY DIFFRACTION (3 Å)