3T1P
Crystal structure of an alpha-1-antitrypsin trimer
Summary for 3T1P
| Entry DOI | 10.2210/pdb3t1p/pdb |
| Descriptor | Alpha-1-antitrypsin (1 entity in total) |
| Functional Keywords | serpin, protease inhibitor, plasma, hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix: P01009 |
| Total number of polymer chains | 1 |
| Total formula weight | 41842.86 |
| Authors | Huntington, J.A.,Yamasaki, M. (deposition date: 2011-07-22, release date: 2011-08-17, Last modification date: 2023-09-13) |
| Primary citation | Yamasaki, M.,Sendall, T.J.,Pearce, M.C.,Whisstock, J.C.,Huntington, J.A. Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer. EMBO Rep., 12:1011-1017, 2011 Cited by PubMed: 21909074DOI: 10.1038/embor.2011.171 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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