3T1N

Structure of human MICROCEPHALIN (MCPH1) TANDEM BRCT domains in complex with a CDC27 phosphopeptide

Summary for 3T1N

Entry DOI	10.2210/pdb3t1n/pdb
Descriptor	Microcephalin, Cdc27 peptide (3 entities in total)
Functional Keywords	tandem brct domains, cell cycle regulation, dna repair, mitosis, phosphorylation, cell cycle-peptide complex, cell cycle/peptide
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton, centrosome: Q8NEM0
Total number of polymer chains	4
Total formula weight	45052.00
Authors	Singh, N.,Thompson, J.R.,Mer, G. (deposition date: 2011-07-22, release date: 2011-11-30, Last modification date: 2023-09-13)
Primary citation	Singh, N.,Wiltshire, T.D.,Thompson, J.R.,Mer, G.,Couch, F.J. Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex. J.Biol.Chem., 287:2854-2862, 2012 Cited by PubMed: 22139841 DOI: 10.1074/jbc.M111.307868 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation