3T1L

Crystal structure of human Galectin-3 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside

Summary for 3T1L

• Entry DOI: 10.2210/pdb3t1l/pdb
• Related: 3T2T 3TIM
• Descriptor: Galectin-3, CHLORIDE ION, methyl 2-O-acetyl-3-O-(4-methylbenzoyl)-beta-D-talopyranoside, ... (4 entities in total)
• Functional Keywords: beta sandwich, sugar binding protein-inhibitor complex, sugar binding protein/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 16444.23

Authors

Blanchard, H.,Collins, P.M. (deposition date: 2011-07-22, release date: 2011-12-28, Last modification date: 2024-03-20)

• Primary citation: Collins, P.M.,Oberg, C.T.,Leffler, H.,Nilsson, U.J.,Blanchard, H.; Taloside inhibitors of galectin-1 and galectin-3; Chem.Biol.Drug Des., 79:339-346, 2012; PubMed: 22136701; DOI: 10.1111/j.1747-0285.2011.01283.x

Experimental method

X-RAY DIFFRACTION (1.6 Å)