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3SRF

Human M1 pyruvate kinase

Summary for 3SRF
Entry DOI10.2210/pdb3srf/pdb
Related3SRD 3SRH
DescriptorPyruvate kinase isozymes M1/M2, PHOSPHATE ION, POTASSIUM ION, ... (7 entities in total)
Functional Keywordstim barrel, phosphoryl transfer, pep binding, cytosol, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P14618
Total number of polymer chains8
Total formula weight485223.93
Authors
Morgan, H.P.,O'Reilly, F.,Palmer, R.,McNae, I.W.,Nowicki, M.W.,Wear, M.A.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D. (deposition date: 2011-07-07, release date: 2012-08-08, Last modification date: 2023-11-15)
Primary citationMorgan, H.P.,O'Reilly, F.,Palmer, R.,McNae, I.W.,Nowicki, M.W.,Wear, M.A.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D.
Allosetric regulation of M2 pyruvate kinase.
To be Published,
Experimental method
X-RAY DIFFRACTION (2.845 Å)
Structure validation

218853

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