3SPH
Inward rectifier potassium channel Kir2.2 I223L mutant in complex with PIP2
Summary for 3SPH
| Entry DOI | 10.2210/pdb3sph/pdb |
| Related | 3SPC 3SPG 3SPI 3SPJ |
| Descriptor | Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (3 entities in total) |
| Functional Keywords | pip, membrane protein, lipid, receptor, metal transport |
| Biological source | Gallus gallus (chicken) |
| Cellular location | Membrane; Multi-pass membrane protein (By similarity): D2YW45 |
| Total number of polymer chains | 1 |
| Total formula weight | 40264.68 |
| Authors | Hansen, S.B.,Tao, X.,MacKinnon, R. (deposition date: 2011-07-01, release date: 2011-08-24, Last modification date: 2023-09-13) |
| Primary citation | Hansen, S.B.,Tao, X.,Mackinnon, R. Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2. Nature, 477:495-498, 2011 Cited by PubMed: 21874019DOI: 10.1038/nature10370 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.003 Å) |
Structure validation
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