3SO6

Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia PTB domain

Summary for 3SO6

Entry DOI	10.2210/pdb3so6/pdb
Descriptor	LDL receptor adaptor protein, Low-density lipoprotein receptor (3 entities in total)
Functional Keywords	ptb, endocytic adaptor, receptor, ldl, ldlr, autosomal recessive hypercholesterolemia, arh, cholesterol, protein binding-protein transport complex, protein binding/protein transport
Biological source	Rattus norvegicus (rat) More
Cellular location	Cytoplasm : D3ZAR1 Cell membrane ; Single-pass type I membrane protein : P01130
Total number of polymer chains	2
Total formula weight	16907.69
Authors	Dvir, H.,Zajonc, D.M. (deposition date: 2011-06-29, release date: 2012-04-18, Last modification date: 2024-02-28)
Primary citation	Dvir, H.,Shah, M.,Girardi, E.,Guo, L.,Farquhar, M.G.,Zajonc, D.M. Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail. Proc.Natl.Acad.Sci.USA, 109:6916-6921, 2012 Cited by PubMed: 22509010 DOI: 10.1073/pnas.1114128109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.37 Å)

Structure validation