3SN6

Crystal structure of the beta2 adrenergic receptor-Gs protein complex

3SN6 の概要

• エントリーDOI: 10.2210/pdb3sn6/pdb
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: seven transmembrane receptor, nanobody, g protein-coupled receptor, gpcr, signal transduction, g protein signaling, signaling protein-hydrolase complex, signaling protein/hydrolase
• 由来する生物種: Bos taurus (Bovine); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 164492.58

構造登録者

Rasmussen, S.G.F.,DeVree, B.T.,Zou, Y.,Kruse, A.C.,Chung, K.Y.,Kobilka, T.S.,Thian, F.S.,Chae, P.S.,Pardon, E.,Calinski, D.,Mathiesen, J.M.,Shah, S.T.A.,Lyons, J.A.,Caffrey, M.,Gellman, S.H.,Steyaert, J.,Skiniotis, G.,Weis, W.I.,Sunahara, R.K.,Kobilka, B.K. (登録日: 2011-06-28, 公開日: 2011-07-20, 最終更新日: 2023-09-13)

• 主引用文献: Rasmussen, S.G.,DeVree, B.T.,Zou, Y.,Kruse, A.C.,Chung, K.Y.,Kobilka, T.S.,Thian, F.S.,Chae, P.S.,Pardon, E.,Calinski, D.,Mathiesen, J.M.,Shah, S.T.,Lyons, J.A.,Caffrey, M.,Gellman, S.H.,Steyaert, J.,Skiniotis, G.,Weis, W.I.,Sunahara, R.K.,Kobilka, B.K.; Crystal structure of the beta2 adrenergic receptor-Gs protein complex; Nature, 477:549-555, 2011; PubMed: 21772288; DOI: 10.1038/nature10361

実験手法

X-RAY DIFFRACTION (3.2 Å)