3SML

Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin A aglycone

Summary for 3SML

Entry DOI	10.2210/pdb3sml/pdb
Related	2O98 3IQU 3LW1
Descriptor	14-3-3 protein sigma, TASK-3 peptide, Fusicoccin A aglycone, ... (6 entities in total)
Functional Keywords	helical protein, phosphoprotein, adapter protein, peptide binding protein, nucleus
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P31947
Total number of polymer chains	2
Total formula weight	27846.89
Authors	Anders, C.,Schumacher, B.,Ottmann, C. (deposition date: 2011-06-28, release date: 2012-07-11, Last modification date: 2023-09-13)
Primary citation	Anders, C.,Higuchi, Y.,Koschinsky, K.,Bartel, M.,Schumacher, B.,Thiel, P.,Nitta, H.,Preisig-Muller, R.,Schlichthorl, G.,Renigunta, V.,Ohkanda, J.,Daut, J.,Kato, N.,Ottmann, C. A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20:583-593, 2013 Cited by PubMed: 23601647 DOI: 10.1016/j.chembiol.2013.03.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation