3SMB
Phenethylisothiocyanate Covalently Bound to Macrophage Migration Inhibitory Factor (MIF)
Summary for 3SMB
| Entry DOI | 10.2210/pdb3smb/pdb |
| Related | 3SMC |
| Descriptor | Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | cytokine, receptor binding, secreted, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted : P14174 |
| Total number of polymer chains | 3 |
| Total formula weight | 37948.98 |
| Authors | Crichlow, G.V.,Lolis, E.J. (deposition date: 2011-06-27, release date: 2012-10-03, Last modification date: 2023-09-13) |
| Primary citation | Crichlow, G.V.,Fan, C.,Keeler, C.,Hodsdon, M.,Lolis, E.J. Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates. Biochemistry, 51:7506-7514, 2012 Cited by PubMed: 22931430DOI: 10.1021/bi3005494 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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