3SHI

Crystal structure of human MMP1 catalytic domain at 2.2 A resolution

Summary for 3SHI

Entry DOI	10.2210/pdb3shi/pdb
Related	1CGE 1HFC 966C
Descriptor	Interstitial collagenase, ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywords	matrix metalloproteinase, paramagnetic restraints, paramagnetic tag, lanthanides, protein refinement, residual dipolar couplings, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space, extracellular matrix : P03956
Total number of polymer chains	3
Total formula weight	53127.11
Authors	Bertini, I.,Calderone, V.,Cerofolini, L.,Fragai, M.,Geraldes, C.F.G.C.,Hermann, P.,Luchinat, C.,Parigi, G.,Teixeira, J. (deposition date: 2011-06-16, release date: 2011-09-21, Last modification date: 2023-09-13)
Primary citation	Bertini, I.,Calderone, V.,Cerofolini, L.,Fragai, M.,Geraldes, C.F.,Hermann, P.,Luchinat, C.,Parigi, G.,Teixeira, J.M. The catalytic domain of MMP-1 studied through tagged lanthanides. Febs Lett., 586:557-567, 2012 Cited by PubMed: 21945315 DOI: 10.1016/j.febslet.2011.09.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation