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3SD0

Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice

Summary for 3SD0
Entry DOI10.2210/pdb3sd0/pdb
DescriptorGlycogen synthase kinase-3 beta, 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywordskinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P49841
Total number of polymer chains2
Total formula weight81114.72
Authors
Mesecar, A.M.,Walters, R.L. (deposition date: 2011-06-08, release date: 2011-08-03, Last modification date: 2024-02-28)
Primary citationMesecar, A.M.,Walters, R.L.
Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice
To be Published,
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

217705

PDB entries from 2024-03-27

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