3S7F

Structural Basis of Substrate Methylation and Inhibition of SMYD2

Summary for 3S7F

Entry DOI	10.2210/pdb3s7f/pdb
Related	3S7B 3S7D 3S7J
Descriptor	N-lysine methyltransferase SMYD2, p53 peptide, S-ADENOSYLMETHIONINE, ... (6 entities in total)
Functional Keywords	methyltransferase, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytosol (By similarity): Q9NRG4
Total number of polymer chains	2
Total formula weight	51895.48
Authors	Ferguson, A.D. (deposition date: 2011-05-26, release date: 2011-08-10, Last modification date: 2024-02-28)
Primary citation	Ferguson, A.D.,Larsen, N.A.,Howard, T.,Pollard, H.,Green, I.,Grande, C.,Cheung, T.,Garcia-Arenas, R.,Cowen, S.,Wu, J.,Godin, R.,Chen, H.,Keen, N. Structural Basis of Substrate Methylation and Inhibition of SMYD2. Structure, 19:1262-1273, 2011 Cited by PubMed: 21782458 DOI: 10.1016/j.str.2011.06.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation