3S78
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
Summary for 3S78
| Entry DOI | 10.2210/pdb3s78/pdb |
| Related | 3S71 3S72 3S73 3S74 3S75 3S76 3S77 |
| Descriptor | Carbonic anhydrase 2, ZINC ION, thiophene-2-sulfonamide, ... (4 entities in total) |
| Functional Keywords | alpha beta, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29462.63 |
| Authors | Snyder, P.W.,Heroux, A.,Whitesides, G.W. (deposition date: 2011-05-26, release date: 2011-10-19, Last modification date: 2024-02-28) |
| Primary citation | Snyder, P.W.,Mecinovic, J.,Moustakas, D.T.,Thomas, S.W.,Harder, M.,Mack, E.T.,Lockett, M.R.,Heroux, A.,Sherman, W.,Whitesides, G.M. Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108:17889-17894, 2011 Cited by PubMed: 22011572DOI: 10.1073/pnas.1114107108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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