3S5F
Crystal structure of human frataxin variant W155F
Summary for 3S5F
| Entry DOI | 10.2210/pdb3s5f/pdb |
| Related | 3S4M 3S5D 3S5E |
| Descriptor | Frataxin, mitochondrial, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | allosteric activator, mitochondrion, alpha beta 2-layer sandwich, unknown function |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q16595 |
| Total number of polymer chains | 2 |
| Total formula weight | 28361.83 |
| Authors | Tsai, C.-L.,Bridwell-Rabb, J.,Barondeau, D.P. (deposition date: 2011-05-23, release date: 2011-06-29, Last modification date: 2023-09-13) |
| Primary citation | Tsai, C.L.,Bridwell-Rabb, J.,Barondeau, D.P. Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex. Biochemistry, 50:6478-6487, 2011 Cited by PubMed: 21671584DOI: 10.1021/bi200666h PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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