3S5D

Crystal structure of human frataxin variant W155A

Summary for 3S5D

Entry DOI	10.2210/pdb3s5d/pdb
Related	3S4M 3S5E 3S5F
Descriptor	Frataxin, mitochondrial, SULFATE ION (3 entities in total)
Functional Keywords	allosteric activator, mitochondrion, alpha beta 2-layer sandwich, unknown function
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q16595
Total number of polymer chains	1
Total formula weight	14176.58
Authors	Tsai, C.-L.,Bridwell-Rabb, J.,Barondeau, D.P. (deposition date: 2011-05-23, release date: 2011-06-29, Last modification date: 2023-09-13)
Primary citation	Tsai, C.L.,Bridwell-Rabb, J.,Barondeau, D.P. Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex. Biochemistry, 50:6478-6487, 2011 Cited by PubMed: 21671584 DOI: 10.1021/bi200666h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation