3RUM

New strategy to analyze structures of glycopeptide antibiotic-target complexes

Summary for 3RUM

Entry DOI	10.2210/pdb3rum/pdb
Related	1ANF 3RUL 3RUN 3VFJ 3VFK
Related PRD ID	PRD_900001
Descriptor	Maltose-binding periplasmic protein, Ristocetin, alpha-D-arabinofuranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-L-rhamnopyranose-(1-6)]beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	antibiotic, glycopeptide, native protein ligation, fusion, carboxymethylation of cysteine, ristocetin, sugar binding protein-antibiotic complex, sugar binding protein/antibiotic
Biological source	Escherichia coli K-12 More
Cellular location	Periplasm: P0AEX9
Total number of polymer chains	3
Total formula weight	46509.67
Authors	Economou, N.J.,Weeks, S.D.,Grasty, K.C.,Nahoum, V.,Loll, P.J. (deposition date: 2011-05-05, release date: 2012-06-06, Last modification date: 2023-12-06)
Primary citation	Economou, N.J.,Nahoum, V.,Weeks, S.D.,Grasty, K.C.,Zentner, I.J.,Townsend, T.M.,Bhuiya, M.W.,Cocklin, S.,Loll, P.J. A carrier protein strategy yields the structure of dalbavancin. J.Am.Chem.Soc., 134:4637-4645, 2012 Cited by PubMed: 22352468 DOI: 10.1021/ja208755j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.851 Å)

Structure validation