3RGQ
Crystal Structure of PTPMT1 in complex with PI(5)P
Summary for 3RGQ
| Entry DOI | 10.2210/pdb3rgq/pdb |
| Related | 3RGO |
| Descriptor | Protein-tyrosine phosphatase mitochondrial 1, (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate (3 entities in total) |
| Functional Keywords | phosphatidylglycerol phosphate (pgp) phosphatase, hydrolase |
| Biological source | Mus musculus (mouse) |
| Cellular location | Mitochondrion inner membrane : Q66GT5 |
| Total number of polymer chains | 1 |
| Total formula weight | 18336.93 |
| Authors | Xiao, J.,Engel, J.L. (deposition date: 2011-04-08, release date: 2011-07-06, Last modification date: 2024-02-21) |
| Primary citation | Xiao, J.,Engel, J.L.,Zhang, J.,Chen, M.J.,Manning, G.,Dixon, J.E. Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc.Natl.Acad.Sci.USA, 108:11860-11865, 2011 Cited by PubMed: 21730175DOI: 10.1073/pnas.1109290108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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