3RG3

Crystal structure of the W5E mutant of human carbonic anhydrase II

Summary for 3RG3

• Entry DOI: 10.2210/pdb3rg3/pdb
• Related: 3RG4 3RG5
• Descriptor: Carbonic anhydrase 2, ZINC ION (3 entities in total)
• Functional Keywords: zinc metalloenzyme, w5e mutation, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 29297.37

Authors

Domsic, J.F.,Robbins, A.H.,McKenna, R. (deposition date: 2011-04-07, release date: 2012-02-22, Last modification date: 2023-09-13)

• Primary citation: Mikulski, R.,Domsic, J.F.,Ling, G.,Tu, C.,Robbins, A.H.,Silverman, D.N.,McKenna, R.; Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.; Arch.Biochem.Biophys., 516:97-102, 2011; PubMed: 22001224; DOI: 10.1016/j.abb.2011.09.011

Experimental method

X-RAY DIFFRACTION (1.903 Å)