3R6C
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179)
Summary for 3R6C
| Entry DOI | 10.2210/pdb3r6c/pdb |
| Related | 3QQS 3QR9 3QS8 3QSA |
| Descriptor | Anthranilate phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | anthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, structural genomics, tb structural genomics consortium, tbsgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 2 |
| Total formula weight | 79425.68 |
| Authors | Castell, A.,Short, F.L.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-03-21, release date: 2012-09-26, Last modification date: 2024-02-21) |
| Primary citation | Castell, A.,Short, F.L.,Evans, G.L.,Cookson, T.V.,Bulloch, E.M.,Joseph, D.D.,Lee, C.E.,Parker, E.J.,Baker, E.N.,Lott, J.S. The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52:1776-1787, 2013 Cited by PubMed: 23363292DOI: 10.1021/bi301387m PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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