3QX8
Crystal structure of MID domain from hAGO2 in complex with m7GpppG
Summary for 3QX8
Entry DOI | 10.2210/pdb3qx8/pdb |
Related | 3LUC |
Descriptor | Protein argonaute-2, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE (3 entities in total) |
Functional Keywords | rossmann-like folde, rna binding, small rna, rna binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, P-body: Q9UKV8 |
Total number of polymer chains | 3 |
Total formula weight | 48388.18 |
Authors | Frank, F.,Fabian, M.R.,Stepinski, J.,Jemielity, J.,Darzynkiewicz, E.,Sonenberg, N.,Nagar, B. (deposition date: 2011-03-01, release date: 2011-04-20, Last modification date: 2023-09-13) |
Primary citation | Frank, F.,Fabian, M.R.,Stepinski, J.,Jemielity, J.,Darzynkiewicz, E.,Sonenberg, N.,Nagar, B. Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain. Embo Rep., 12:415-420, 2011 Cited by PubMed: 21475248DOI: 10.1038/embor.2011.48 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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